Porcine reproductive and respiratory syndrome (PRRS) remains one of the most consequential animal health challenges facing the U.S. swine industry—driving profound animal suffering, caregiver stress, and more than $1 billion in annual economic losses. In this timely JAVMA Viewpoint, the authors lay out a clear, experience-based road map for national PRRS elimination, grounded in science, field validation, and lessons learned from past eradication successes such as pseudorabies. Framed around the shared vision of “A World Without PRRS,” the paper identifies 11 practical tactics to move from aspiration to action—emphasizing producer leadership, veterinary engagement, education, surveillance, communication, and sustained collaboration to protect animal well-being, rural livelihoods, and U.S. agricultural competitiveness.    

Author acknowledgment, NAFV involvement, and RVAP importance 

 This paper reflects the strength of collaboration across the full spectrum of animal health, with authors bringing perspectives that span private and corporate swine practice, pork production and pig farming, academia, diagnostic laboratories, state animal health leadership, and federal veterinary service. Notably, the National Association of Federal Veterinarians (NAFV) played an active role in this effort, underscoring the importance of federal veterinarians as partners in producer-led disease elimination initiatives. The authors also highlight the critical need for a strong and sustainable rural veterinary workforce, explicitly reinforcing the importance of the USDA Rural Veterinary Action Plan (RVAP) as a foundational element for long-term success. Together, these diverse voices send a unified message: eliminating PRRS is achievable—but only through coordinated action that values people, animals, and the professionals who serve them.